Comparative Effects of <i>Allium sativum</i> (Garlic) and <i>Allium porrum</i> (Leek) on Lacerated Wound Isolates

Background: The pharmacological properties of Allium family have been reported to include antibacterial, antioxidant, anticancer, anti-aging and antilipidemic properties. This investigation was conducted evaluate the antibacterial ethanolic aqueous extracts sativum porrum on both Gram-positive Gram-negative organisms from chronic wound infections. Methods: Ten (10) isolates were obtained infected open wounds patients at Chukwuemeka Odumegwu Ojukwu University teaching Hospital Amakwu Nnamdi Azikiwe Teaching Nnewi, Anambra state, Nigeria. Gram reaction other biochemical tests namely: Indole, Citrate, Catalase, coagulase oxidase done for identification isolates. are K. pneumoniae (three), S. aureus (two), Enterococcus P. aeruginosa (two) E. coli (one). determined using agar well diffusion method while Gentamicin (10 mcg) Tetracycline (30 used as positive controls. Result: results study showed that extract (500 mg/ml 250 mg/ml) respectively had an inhibitory effect all bacteria under study, except a strain which also resistant conventional antibiotics (Gentamicin Tetracycline) ethonolic inhibited one coli. Worthy note is plants two (2) strains (1) Tetracycline. combination these plant did not produce any synergistic effects. Conclusion: present provides evidence possess antibacteria could serve alternatives in treatment bacterial infections wounds.